Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review.

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Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review.

Category : Antiinflamatorio

Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review.

Cureus. 2017 Nov 29;9(11):e1888

Authors: Naveed S, Amray A, Waqas A, Chaudhary AM, Azeem MW

Abstract
N-acetylcysteine (NAC) is a well-known antidote for acetaminophen toxicity and is easily available over the counter. It has antioxidant and anti-inflammatory properties and an established tolerance and safety profile. Owing to its neuroprotective effects, its clinical use has recently expanded to include the treatment of different psychiatric and non-psychiatric disorders. Although a number of randomized controlled trials have documented the clinical evidence for NAC, there are no reviews that summarize the evidence. The present scoping review summarizes the study designs, the patient characteristics, the evidence and the limitations in randomized controlled trials designed to explore the efficacy of NAC for psychiatric conditions in the pediatric population.

PMID: 29392100 [PubMed]

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